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DNMT3B System Dysregulation Contributes to the Hypomethylated State in Ischaemic Human Hearts

A controversial understanding of the state of the DNA methylation machinery exists in ischaemic cardiomyopathy (ICM). Moreover, its relationship to other epigenetic alterations is incomplete. Therefore, we carried out an in-depth study of the DNA methylation process in human cardiac tissue. We showe...

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Detalles Bibliográficos
Autores principales: Tarazón, Estefanía, Pérez-Carrillo, Lorena, Giménez-Escamilla, Isaac, García-Manzanares, María, Martínez-Dolz, Luis, Portolés, Manuel, Roselló-Lletí, Esther
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9029641/
https://www.ncbi.nlm.nih.gov/pubmed/35453616
http://dx.doi.org/10.3390/biomedicines10040866