Targeted Degradation of 53BP1 Using Ubiquitin Variant Induced Proximity

In recent years, researchers have leveraged the ubiquitin-proteasome system (UPS) to induce selective degradation of proteins by E3 ubiquitin ligases, which has great potential as novel therapeutics for human diseases, including cancer and neurodegenerative disorders. However, despite extensive effo...

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Detalles Bibliográficos
Autores principales: Aminu, Bayonle, Fux, Julia, Mallette, Evan, Petersen, Nathaniel, Zhang, Wei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9029692/
https://www.ncbi.nlm.nih.gov/pubmed/35454069
http://dx.doi.org/10.3390/biom12040479

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9029692/
https://www.ncbi.nlm.nih.gov/pubmed/35454069
http://dx.doi.org/10.3390/biom12040479

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