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Crystal Structure of an SSB Protein from Salmonella enterica and Its Inhibition by Flavanonol Taxifolin

Single-stranded DNA (ssDNA)-binding proteins (SSBs) play a central role in cells by participating in DNA metabolism, including replication, repair, recombination, and replication fork restart. SSBs are essential for cell survival and thus an attractive target for potential anti-pathogen chemotherapy...

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Detalles Bibliográficos
Autores principales: Lin, En-Shyh, Huang, Yen-Hua, Luo, Ren-Hong, Basharat, Zarrin, Huang, Cheng-Yang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9029707/
https://www.ncbi.nlm.nih.gov/pubmed/35457218
http://dx.doi.org/10.3390/ijms23084399