Improvement of Biocatalytic Properties and Cytotoxic Activity of L-Asparaginase from Rhodospirillum rubrum by Conjugation with Chitosan-Based Cationic Polyelectrolytes

L-asparaginases (L-ASNases, EC 3.5.1.1) are a family of enzymes that are widely used for the treatment of lymphoblastic leukemias. L-ASNase from Rhodospirillum rubrum (RrA) has a low molecular weight, low glutaminase activity, and low immunogenicity, making it a promising enzyme for antitumor drug d...

Descripción completa

Detalles Bibliográficos
Autores principales: Dobryakova, Natalia V., Zhdanov, Dmitry D., Sokolov, Nikolay N., Aleksandrova, Svetlana S., Pokrovskaya, Marina V., Kudryashova, Elena V.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9029710/
https://www.ncbi.nlm.nih.gov/pubmed/35455403
http://dx.doi.org/10.3390/ph15040406

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9029710/
https://www.ncbi.nlm.nih.gov/pubmed/35455403
http://dx.doi.org/10.3390/ph15040406

Ejemplares similares