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Improvement of Biocatalytic Properties and Cytotoxic Activity of L-Asparaginase from Rhodospirillum rubrum by Conjugation with Chitosan-Based Cationic Polyelectrolytes

L-asparaginases (L-ASNases, EC 3.5.1.1) are a family of enzymes that are widely used for the treatment of lymphoblastic leukemias. L-ASNase from Rhodospirillum rubrum (RrA) has a low molecular weight, low glutaminase activity, and low immunogenicity, making it a promising enzyme for antitumor drug d...

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Detalles Bibliográficos
Autores principales:	Dobryakova, Natalia V., Zhdanov, Dmitry D., Sokolov, Nikolay N., Aleksandrova, Svetlana S., Pokrovskaya, Marina V., Kudryashova, Elena V.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2022
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9029710/ https://www.ncbi.nlm.nih.gov/pubmed/35455403 http://dx.doi.org/10.3390/ph15040406

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