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Towards Kinase Inhibitor Therapies for Fragile X Syndrome: Tweaking Twists in the Autism Spectrum Kinase Signaling Network

Absence of the Fragile X Messenger Ribonucleoprotein 1 (FMRP) causes autism spectrum disorders and intellectual disability, commonly referred to as the Fragile X syndrome. FMRP is a negative regulator of protein translation and is essential for neuronal development and synapse formation. FMRP is a t...

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Detalles Bibliográficos
Autores principales: D’Incal, Claudio, Broos, Jitse, Torfs, Thierry, Kooy, R. Frank, Vanden Berghe, Wim
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9029738/
https://www.ncbi.nlm.nih.gov/pubmed/35456004
http://dx.doi.org/10.3390/cells11081325