Impact of Different [Tc(N)PNP]-Scaffolds on the Biological Properties of the Small cRGDfK Peptide: Synthesis, In Vitro and In Vivo Evaluations

Background: The [(99m)Tc][Tc(N)(PNP)] system, where PNP is a bisphosphinoamine, is an interesting platform for the development of tumor ‘receptor-specific’ agents. Here, we compared the reactivity and impact of three [Tc(N)(PNP)] frameworks on the stability, receptor targeting properties, biodistrib...

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Detalles Bibliográficos
Autores principales: Salvarese, Nicola, Carpanese, Debora, Meléndez-Alafort, Laura, De Nardo, Laura, Calderan, Andrea, Biondi, Barbara, Ruzza, Paolo, Rosato, Antonio, Bolzati, Cristina
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9029856/
https://www.ncbi.nlm.nih.gov/pubmed/35458745
http://dx.doi.org/10.3390/molecules27082548

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9029856/
https://www.ncbi.nlm.nih.gov/pubmed/35458745
http://dx.doi.org/10.3390/molecules27082548

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