Cargando…

Protective Effects against the Development of Alzheimer’s Disease in an Animal Model through Active Immunization with Methionine-Sulfoxide Rich Protein Antigen

The brain during Alzheimer’s disease (AD) is under severe oxidative attack by reactive oxygen species that may lead to methionine oxidation. Oxidation of the sole methionine (Met35) of beta-amyloid (Aβ), and possibly methionine residues of other extracellular proteins, may be one of the earliest eve...

Descripción completa

Detalles Bibliográficos
Autores principales: Smith, Adam S., Gossman, Kyle R., Dykstra, Benjamin, Gao, Fei Philip, Moskovitz, Jackob
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9029927/
https://www.ncbi.nlm.nih.gov/pubmed/35453459
http://dx.doi.org/10.3390/antiox11040775