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UPF1 Inhibits Hepatocellular Carcinoma Growth through DUSP1/p53 Signal Pathway

Human hepatocellular carcinoma (HCC) has a high mortality rate because of the dearth of effective treatments. Multiple studies have shown that overexpression of UPF1, a key nonsense-mediated mRNA decay (NMD) factor, reduces HCC growth through various cell signaling pathways. However, the mechanism b...

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Detalles Bibliográficos
Autores principales: Lee, Suman, Hwang, Yukyung, Kim, Tae Hun, Jeong, Jaemin, Choi, Dongho, Hwang, Jungwook
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9029930/
https://www.ncbi.nlm.nih.gov/pubmed/35453543
http://dx.doi.org/10.3390/biomedicines10040793