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UPF1 Inhibits Hepatocellular Carcinoma Growth through DUSP1/p53 Signal Pathway
Human hepatocellular carcinoma (HCC) has a high mortality rate because of the dearth of effective treatments. Multiple studies have shown that overexpression of UPF1, a key nonsense-mediated mRNA decay (NMD) factor, reduces HCC growth through various cell signaling pathways. However, the mechanism b...
Autores principales: | Lee, Suman, Hwang, Yukyung, Kim, Tae Hun, Jeong, Jaemin, Choi, Dongho, Hwang, Jungwook |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9029930/ https://www.ncbi.nlm.nih.gov/pubmed/35453543 http://dx.doi.org/10.3390/biomedicines10040793 |
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