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N-1 Perfusion Platform Development Using a Capacitance Probe for Biomanufacturing

Fed-batch process intensification with a significantly shorter culture duration or higher titer for monoclonal antibody (mAb) production by Chinese hamster ovary (CHO) cells can be achieved by implementing perfusion operation at the N-1 stage for biomanufacturing. N-1 perfusion seed with much higher...

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Detalles Bibliográficos
Autores principales: Rittershaus, Emily S. C., Rehmann, Matthew S., Xu, Jianlin, He, Qin, Hill, Charles, Swanberg, Jeffrey, Borys, Michael C., Li, Zheng-Jian, Khetan, Anurag
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9029935/
https://www.ncbi.nlm.nih.gov/pubmed/35447688
http://dx.doi.org/10.3390/bioengineering9040128