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N-1 Perfusion Platform Development Using a Capacitance Probe for Biomanufacturing
Fed-batch process intensification with a significantly shorter culture duration or higher titer for monoclonal antibody (mAb) production by Chinese hamster ovary (CHO) cells can be achieved by implementing perfusion operation at the N-1 stage for biomanufacturing. N-1 perfusion seed with much higher...
Autores principales: | Rittershaus, Emily S. C., Rehmann, Matthew S., Xu, Jianlin, He, Qin, Hill, Charles, Swanberg, Jeffrey, Borys, Michael C., Li, Zheng-Jian, Khetan, Anurag |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9029935/ https://www.ncbi.nlm.nih.gov/pubmed/35447688 http://dx.doi.org/10.3390/bioengineering9040128 |
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