5-O-(N-Boc-l-Alanine)-Renieramycin T Induces Cancer Stem Cell Apoptosis via Targeting Akt Signaling

Cancer stem cells (CSCs) drive aggressiveness and metastasis by utilizing stem cell-related signals. In this study, 5-O-(N-Boc-l-alanine)-renieramycin T (OBA-RT) was demonstrated to suppress CSC signals and induce apoptosis. OBA-RT exerted cytotoxic effects with a half-maximal inhibitory concentrati...

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Detalles Bibliográficos
Autores principales: Suksamai, Darinthip, Racha, Satapat, Sriratanasak, Nicharat, Chaotham, Chatchai, Aphicho, Kanokpol, Lin, Aye Chan Khine, Chansriniyom, Chaisak, Suwanborirux, Khanit, Chamni, Supakarn, Chanvorachote, Pithi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9029977/
https://www.ncbi.nlm.nih.gov/pubmed/35447911
http://dx.doi.org/10.3390/md20040235

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9029977/
https://www.ncbi.nlm.nih.gov/pubmed/35447911
http://dx.doi.org/10.3390/md20040235

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