In silico identification of potential SARS COV-2 2′-O-methyltransferase inhibitor: fragment-based screening approach and MM-PBSA calculations

In the present era, there are many efforts trying to face the emerging and successive waves of the COVID-19 pandemic. This has led to considering new and unusual targets for SARS CoV-2. 2′-O-Methyltransferase (nsp16) is a key and attractive target in the SARS CoV-2 life cycle since it is responsible...

Descripción completa

Detalles Bibliográficos
Autores principales: El Hassab, Mahmoud A., Ibrahim, Tamer M., Shoun, Aly A., Al-Rashood, Sara T., Alkahtani, Hamad M., Alharbi, Amal, Eskandrani, Razan O., Eldehna, Wagdy M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Royal Society of Chemistry 2021
Materias:
Chemistry
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9029993/
https://www.ncbi.nlm.nih.gov/pubmed/35481212
http://dx.doi.org/10.1039/d1ra01809d

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9029993/
https://www.ncbi.nlm.nih.gov/pubmed/35481212
http://dx.doi.org/10.1039/d1ra01809d

Ejemplares similares