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Activation of TRPV4 Induces Exocytosis and Ferroptosis in Human Melanoma Cells

TRPV4 (transient receptor potential vanilloid 4), a calcium permeable TRP ion channel, is known to play a key role in endocytosis. However, whether it contributes to exocytosis remains unclear. Here, we report that activation of TRPV4 induced massive exocytosis in both melanoma A375 cell and heterol...

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Detalles Bibliográficos
Autores principales: Li, Mei, Zheng, Jiaojiao, Wu, Tian, He, Yulin, Guo, Jing, Xu, Jiao, Gao, Chuanzhou, Qu, Shuxian, Zhang, Qianyi, Zhao, Jiayu, Cheng, Wei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9030060/
https://www.ncbi.nlm.nih.gov/pubmed/35456964
http://dx.doi.org/10.3390/ijms23084146