Protease activity sensors enable real-time treatment response monitoring in lymphangioleiomyomatosis

BACKGROUND: Biomarkers of disease progression and treatment response are urgently needed for patients with lymphangioleiomyomatosis (LAM). Activity-based nanosensors, an emerging biosensor class, detect dysregulated proteases in vivo and release a reporter to provide a urinary readout of disease. Be...

Descripción completa

Detalles Bibliográficos
Autores principales: Kirkpatrick, Jesse D., Soleimany, Ava P., Dudani, Jaideep S., Liu, Heng-Jia, Lam, Hilaire C., Priolo, Carmen, Henske, Elizabeth P., Bhatia, Sangeeta N.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: European Respiratory Society 2022
Materias:
Original Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9030069/
https://www.ncbi.nlm.nih.gov/pubmed/34561286
http://dx.doi.org/10.1183/13993003.00664-2021

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9030069/
https://www.ncbi.nlm.nih.gov/pubmed/34561286
http://dx.doi.org/10.1183/13993003.00664-2021

Ejemplares similares