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Protease activity sensors enable real-time treatment response monitoring in lymphangioleiomyomatosis
BACKGROUND: Biomarkers of disease progression and treatment response are urgently needed for patients with lymphangioleiomyomatosis (LAM). Activity-based nanosensors, an emerging biosensor class, detect dysregulated proteases in vivo and release a reporter to provide a urinary readout of disease. Be...
Autores principales: | Kirkpatrick, Jesse D., Soleimany, Ava P., Dudani, Jaideep S., Liu, Heng-Jia, Lam, Hilaire C., Priolo, Carmen, Henske, Elizabeth P., Bhatia, Sangeeta N. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
European Respiratory Society
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9030069/ https://www.ncbi.nlm.nih.gov/pubmed/34561286 http://dx.doi.org/10.1183/13993003.00664-2021 |
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