Methylglyoxal Impairs Sister Chromatid Separation in Lymphocytes

The accurate segregation of sister chromatids is complex, and errors that arise throughout this process can drive chromosomal instability and tumorigenesis. We recently showed that methylglyoxal (MGO), a glycolytic by-product, can cause chromosome missegregation events in lymphocytes. However, the u...

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Detalles Bibliográficos
Autores principales: Donnellan, Leigh, Young, Clifford, Simpson, Bradley S., Dhillon, Varinderpal S., Costabile, Maurizio, Hoffmann, Peter, Fenech, Michael, Deo, Permal
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9030103/
https://www.ncbi.nlm.nih.gov/pubmed/35456956
http://dx.doi.org/10.3390/ijms23084139

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9030103/
https://www.ncbi.nlm.nih.gov/pubmed/35456956
http://dx.doi.org/10.3390/ijms23084139

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