Natural Phaeosphaeride A Derivatives Overcome Drug Resistance of Tumor Cells and Modulate Signaling Pathways

In the present study, natural phaeosphaeride A (PPA) derivatives are synthesized. Anti-tumor studies are carried out on the PC3, K562, HCT-116, THP-1, MCF-7, A549, NCI-H929, Jurkat, and RPMI8226 tumor cell lines, and on the human embryonic kidney (HEK293) cell line. All the compounds synthesized tur...

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Detalles Bibliográficos
Autores principales: Abzianidze, Victoria, Moiseeva, Natalia, Suponina, Diana, Zakharenkova, Sofya, Rogovskaya, Nadezhda, Laletina, Lidia, Holder, Alvin A., Krivorotov, Denis, Bogachenkov, Alexander, Garabadzhiu, Alexander, Ukolov, Anton, Kosorukov, Vyacheslav
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9030166/
https://www.ncbi.nlm.nih.gov/pubmed/35455394
http://dx.doi.org/10.3390/ph15040395

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9030166/
https://www.ncbi.nlm.nih.gov/pubmed/35455394
http://dx.doi.org/10.3390/ph15040395

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