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Dual-Functional Polymeric Micelles Co-Loaded with Antineoplastic Drugs and Tyrosine Kinase Inhibitor for Combination Therapy in Colorectal Cancer

The aim of this research was to evaluate the receptor tyrosine kinase inhibitor Sunitinib combined with SN-38 in polymeric micelles for antitumor efficacy in colorectal cancer. First, SN-38 and Sunitinib co-loaded micelles were developed and characterized. We studied cell viability and cellular upta...

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Detalles Bibliográficos
Autores principales: Shih, Ying-Hsia, Peng, Cheng-Liang, Chiang, Ping-Fang, Shieh, Ming-Jium
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9030189/
https://www.ncbi.nlm.nih.gov/pubmed/35456602
http://dx.doi.org/10.3390/pharmaceutics14040768