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Alterations in Proteostasis System Components in Peripheral Blood Mononuclear Cells in Parkinson Disease: Focusing on the HSP70 and p62 Levels

Parkinson disease (PD) is attributed to a proteostasis disorder mediated by α-synuclein accumulating in a specific brain region. PD manifestation is often related to extraneuronal alterations, some of which could be used as diagnostic or prognostic PD biomarkers. In this work, we studied the shifts...

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Detalles Bibliográficos
Autores principales: Vavilova, Julia D., Boyko, Anna A., Troyanova, Natalya I., Ponomareva, Natalya V., Fokin, Vitaly F., Fedotova, Ekaterina Y., Streltsova, Maria A., Kust, Sofya A., Grechikhina, Maria V., Shustova, Olga A., Azhikina, Tatyana L., Kovalenko, Elena I., Sapozhnikov, Alexander M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9030208/
https://www.ncbi.nlm.nih.gov/pubmed/35454081
http://dx.doi.org/10.3390/biom12040493