Cargando…

Alterations in Proteostasis System Components in Peripheral Blood Mononuclear Cells in Parkinson Disease: Focusing on the HSP70 and p62 Levels

Parkinson disease (PD) is attributed to a proteostasis disorder mediated by α-synuclein accumulating in a specific brain region. PD manifestation is often related to extraneuronal alterations, some of which could be used as diagnostic or prognostic PD biomarkers. In this work, we studied the shifts...

Descripción completa

Detalles Bibliográficos
Autores principales:	Vavilova, Julia D., Boyko, Anna A., Troyanova, Natalya I., Ponomareva, Natalya V., Fokin, Vitaly F., Fedotova, Ekaterina Y., Streltsova, Maria A., Kust, Sofya A., Grechikhina, Maria V., Shustova, Olga A., Azhikina, Tatyana L., Kovalenko, Elena I., Sapozhnikov, Alexander M.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2022
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9030208/ https://www.ncbi.nlm.nih.gov/pubmed/35454081 http://dx.doi.org/10.3390/biom12040493

Ejemplares similares

Reduced Immunosenescence of Peripheral Blood T Cells in Parkinson’s Disease with CMV Infection Background
por: Vavilova, Julia D., et al.
Publicado: (2021)

Increased Susceptibility of the CD57(−) NK Cells Expressing KIR2DL2/3 and NKG2C to iCasp9 Gene Retroviral Transduction and the Relationships with Proliferative Potential, Activation Degree, and Death Induction Response
por: Palamarchuk, Anastasia I., et al.
Publicado: (2021)

HLA-DR-Positive NK Cells Expand in Response to Mycobacterium Tuberculosis Antigens and Mediate Mycobacteria-Induced T Cell Activation
por: Kust, Sofya A., et al.
Publicado: (2021)

Similarity and Differences in Inflammation-Related Characteristics of the Peripheral Immune System of Patients with Parkinson’s and Alzheimer’s Diseases
por: Boyko, Anna A., et al.
Publicado: (2017)

The Biological Role and Therapeutic Potential of NK Cells in Hematological and Solid Tumors
por: Velichinskii, Rodion A., et al.
Publicado: (2021)

Phenotypic Changes in T and NK Cells Induced by Sputnik V Vaccination
por: Boyko, Anna A., et al.
Publicado: (2023)

Recurrent Stimulation of Natural Killer Cell Clones with K562 Expressing Membrane-Bound Interleukin-21 Affects Their Phenotype, Interferon-γ Production, and Lifespan
por: Streltsova, Maria A., et al.
Publicado: (2019)

Telomerase Reverse Transcriptase Increases Proliferation and Lifespan of Human NK Cells without Immortalization
por: Streltsova, Maria A., et al.
Publicado: (2021)

ROS production, intracellular HSP70 levels and their relationship in human neutrophils: effects of age
por: Kovalenko, Elena I., et al.
Publicado: (2014)

A Novel Approach to Anticancer Therapy: Molecular Modules Based on the Barnase:Barstar Pair for Targeted Delivery of HSP70 to Tumor Cells
por: Sapozhnikov, A. M., et al.
Publicado: (2018)

Alterations in the CD56(−) and CD56(+) T Cell Subsets during COVID-19
por: Vavilova, Julia D., et al.
Publicado: (2023)

Coordinated Loss and Acquisition of NK Cell Surface Markers Accompanied by Generalized Cytokine Dysregulation in COVID-19
por: Ustiuzhanina, Maria O., et al.
Publicado: (2023)

Dimorphism of HLA-E and Its Disease Association
por: Kanevskiy, Leonid, et al.
Publicado: (2019)

Surface NKG2C Identifies Differentiated αβT-Cell Clones Expanded in Peripheral Blood
por: Kovalenko, Elena I., et al.
Publicado: (2021)

Analysis of NK cell clones obtained using interleukin-2 and gene-modified K562 cells revealed the ability of “senescent” NK cells to lose CD57 expression and start expressing NKG2A
por: Streltsova, Maria A., et al.
Publicado: (2018)

The Role of O-Antigen in LPS-Induced Activation of Human NK Cells
por: Kanevskiy, Leonid M., et al.
Publicado: (2019)

Epithelial-Immune Cell Crosstalk Determines the Activation of Immune Cells In Vitro by the Human Cathelicidin LL-37 at Low Physiological Concentrations
por: Bogdanov, Ivan V., et al.
Publicado: (2023)

Multiple Actions of Telomerase Reverse Transcriptase in Cell Death Regulation
por: Palamarchuk, Anastasia I., et al.
Publicado: (2023)

Age-dependent effect of Alzheimer’s risk variant of CLU on EEG alpha rhythm in non-demented adults
por: Ponomareva, Natalya, et al.
Publicado: (2013)

Neuronal Hyperactivation in EEG Data during Cognitive Tasks Is Related to the Apolipoprotein J/Clusterin Genotype in Nondemented Adults
por: Ponomareva, Natalya V., et al.
Publicado: (2023)

Genetic Association Between Alzheimer’s Disease Risk Variant of the PICALM Gene and EEG Functional Connectivity in Non-demented Adults
por: Ponomareva, Natalya, et al.
Publicado: (2020)

Genetic association of apolipoprotein E genotype with EEG alpha rhythm slowing and functional brain network alterations during normal aging
por: Ponomareva, Natalya V., et al.
Publicado: (2022)

The autophagy receptor p62/SQST-1 promotes proteostasis and longevity in C. elegans by inducing autophagy
por: Kumsta, Caroline, et al.
Publicado: (2019)

The Interactive Effect of Genetic and Epigenetic Variations in FKBP5 and ApoE Genes on Anxiety and Brain EEG Parameters
por: Kuznetsova, Irina L., et al.
Publicado: (2022)

HSF1 stress response pathway regulates autophagy receptor SQSTM1/p62-associated proteostasis
por: Watanabe, Yoshihisa, et al.
Publicado: (2016)

Rodent Models of Audiogenic Epilepsy: Genetic Aspects, Advantages, Current Problems and Perspectives
por: Garbuz, David G., et al.
Publicado: (2022)

Proteostasis Response to Protein Misfolding in Controlled Hypertension
por: Teixeira, Manuel, et al.
Publicado: (2022)

Immunomodulatory Effects of Lactobacillus plantarum Lp62 on Intestinal Epithelial and Mononuclear Cells
por: Ferreira dos Santos, Thalis, et al.
Publicado: (2016)

Small Molecule Proteostasis Regulators for Protein Conformational Diseases
por: Calamini, Barbara, et al.
Publicado: (2011)

Host proteostasis modulates influenza evolution
por: Phillips, Angela M, et al.
Publicado: (2017)

Regulation of mitochondrial proteostasis by the proton gradient
por: Patron, Maria, et al.
Publicado: (2022)

The Contribution of the 20S Proteasome to Proteostasis
por: Kumar Deshmukh, Fanindra, et al.
Publicado: (2019)

A Year at the Forefront of Proteostasis and Aging
por: Thompson, Maximilian A., et al.
Publicado: (2023)

Murine Intraepithelial Dendritic Cells Interact With Phagocytic Cells During Aspergillus fumigatus-Induced Inflammation
por: Bogorodskiy, Andrey O., et al.
Publicado: (2020)

Low-energy Coulomb excitation of $^{62}$Fe and $^{62}$Mn following in-beam decay of $^{62}$Mn
por: Gaffney, L P, et al.
Publicado: (2015)

Ribosome-associated chaperones act as proteostasis sentinels
por: Kirstein-Miles, Janine, et al.
Publicado: (2013)

Exosomal and non-exosomal miRNA expression levels in patients with HCV-related cirrhosis and liver cancer
por: Petkevich, Alisa A., et al.
Publicado: (2021)

LRRK2 and Proteostasis in Parkinson’s Disease
por: Pérez-Carrión, María Dolores, et al.
Publicado: (2022)

The molecular basis of cereal grain proteostasis
por: Cao, Hui, et al.
Publicado: (2022)

Dysfunction of Cellular Proteostasis in Parkinson’s Disease
por: Lehtonen, Šárka, et al.
Publicado: (2019)

Cannot write session to /tmp/vufind_sessions/sess_vevssu2hdenkm4rdqf2had2efh