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Studies on Preformulation and Formulation of JIN-001 Liquisolid Tablet with Enhanced Solubility

This study aimed to develop a heat shock protein 90 (Hsp90) inhibitor liquisolid tablet with improved solubility to overcome low bioavailability issues. As an active pharmaceutical ingredient (API), JIN-001, a novel Hsp90 inhibitor, was reported to have substantial in vitro antiproliferative and in...

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Detalles Bibliográficos
Autores principales: Kim, Han-Sol, Kim, Chang-Min, Jo, An-Na, Kim, Joo-Eun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9030333/
https://www.ncbi.nlm.nih.gov/pubmed/35455409
http://dx.doi.org/10.3390/ph15040412