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Neuroprotective Effect of Ramipril Is Mediated by AT2 in a Mouse MODEL of Paclitaxel-Induced Peripheral Neuropathy

Paclitaxel (PTX)-induced peripheral neuropathy (PIPN) induces numerous symptoms affecting patient quality of life, leading to decreased doses or even to cessation of anticancer therapy. Previous studies have reported that a widely used drug, ramipril, improves neuroprotection in several rodent model...

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Detalles Bibliográficos
Autores principales: Bouchenaki, Hichem, Bernard, Amandine, Bessaguet, Flavien, Frachet, Simon, Richard, Laurence, Sturtz, Franck, Magy, Laurent, Bourthoumieu, Sylvie, Demiot, Claire, Danigo, Aurore
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9030366/
https://www.ncbi.nlm.nih.gov/pubmed/35456682
http://dx.doi.org/10.3390/pharmaceutics14040848