The Discovery of Potent SHP2 Inhibitors with Anti-Proliferative Activity in Breast Cancer Cell Lines

Despite available treatments, breast cancer is the leading cause of cancer-related death. Knowing that the tyrosine phosphatase SHP2 is a regulator in tumorigenesis, developing inhibitors of SHP2 in breast cells is crucial. Our study investigated the effects of new compounds, purchased from NSC, on...

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Detalles Bibliográficos
Autores principales: Ghemrawi, Rose, Khair, Mostafa, Hasan, Shaima, Aldulaymi, Raghad, AlNeyadi, Shaikha S., Atatreh, Noor, Ghattas, Mohammad A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9030381/
https://www.ncbi.nlm.nih.gov/pubmed/35457286
http://dx.doi.org/10.3390/ijms23084468

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9030381/
https://www.ncbi.nlm.nih.gov/pubmed/35457286
http://dx.doi.org/10.3390/ijms23084468

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