In Silico Screen Identifies a New Family of Agonists for the Bacterial Mechanosensitive Channel MscL

MscL is a highly conserved mechanosensitive channel found in the majority of bacterial species, including pathogens. It functions as a biological emergency release valve, jettisoning solutes from the cytoplasm upon acute hypoosmotic stress. It opens the largest known gated pore and has been heralded...

Descripción completa

Detalles Bibliográficos
Autores principales: Wray, Robin, Blount, Paul, Wang, Junmei, Iscla, Irene
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9030384/
https://www.ncbi.nlm.nih.gov/pubmed/35453186
http://dx.doi.org/10.3390/antibiotics11040433

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9030384/
https://www.ncbi.nlm.nih.gov/pubmed/35453186
http://dx.doi.org/10.3390/antibiotics11040433

Ejemplares similares