Evaluation of Host Cell Impurity Effects on the Performance of Sterile Filtration Processes for Therapeutic Viruses

Efficient downstream processing represents a significant challenge in the rapidly developing field of therapeutic viruses. While it is known that the terminal sterile filtration step can be a major cause of product loss, there is little known about the effect of host cell impurities (DNA and protein...

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Detalles Bibliográficos
Autores principales: Wright, Evan, Kawka, Karina, Medina, Maria Fe C., Latulippe, David R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9030567/
https://www.ncbi.nlm.nih.gov/pubmed/35448330
http://dx.doi.org/10.3390/membranes12040359

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9030567/
https://www.ncbi.nlm.nih.gov/pubmed/35448330
http://dx.doi.org/10.3390/membranes12040359

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