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Heterologous prime-boost vaccination based on Polymorphic protein D protects against intravaginal Chlamydia trachomatis infection in mice

The control of the worldwide spread of sexually transmitted Chlamydia trachomatis (Ct) infection urgently demands the development of a preventive vaccine. In this work, we designed a vaccine based on a fragment of polymorphic protein D (FPmpD) that proved to be immunogenic enough to generate a robus...

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Detalles Bibliográficos
Autores principales: Russi, Romina Cecilia, Del Balzo, Diego, Luján, Agustín, Reidel, Ivana Gabriela, García, María Inés, Veaute, Carolina, Damiani, María Teresa
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9030682/
https://www.ncbi.nlm.nih.gov/pubmed/35459778
http://dx.doi.org/10.1038/s41598-022-10633-x