Toxicokinetics of β-Amanitin in Mice and In Vitro Drug–Drug Interaction Potential

The toxicokinetics of β-amanitin, a toxic bicyclic octapeptide present abundantly in Amanitaceae mushrooms, was evaluated in mice after intravenous (iv) and oral administration. The area under plasma concentration curves (AUC) following iv injection increased in proportion to doses of 0.2, 0.4, and...

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Detalles Bibliográficos
Autores principales: Bang, Young Yoon, Song, Im-Sook, Lee, Min Seo, Lim, Chang Ho, Cho, Yong-Yeon, Lee, Joo Young, Kang, Han Chang, Lee, Hye Suk
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9030691/
https://www.ncbi.nlm.nih.gov/pubmed/35456608
http://dx.doi.org/10.3390/pharmaceutics14040774

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9030691/
https://www.ncbi.nlm.nih.gov/pubmed/35456608
http://dx.doi.org/10.3390/pharmaceutics14040774

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