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Escalated (Dependent) Oxycodone Self-Administration Is Associated with Cognitive Impairment and Transcriptional Evidence of Neurodegeneration in Human Immunodeficiency Virus (HIV) Transgenic Rats

Substance use disorder is associated with accelerated disease progression in people with human immunodeficiency virus (HIV; PWH). Problem opioid use, including high-dose opioid therapy, prescription drug misuse, and opioid abuse, is high and increasing in the PWH population. Oxycodone is a broadly p...

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Detalles Bibliográficos
Autores principales: Fu, Yu, Lorrai, Irene, Zorman, Barry, Mercatelli, Daniele, Shankula, Chase, Marquez Gaytan, Jorge, Lefebvre, Celine, de Guglielmo, Giordano, Kim, Hyunjae Ryan, Sumazin, Pavel, Giorgi, Federico M., Repunte-Canonigo, Vez, Sanna, Pietro Paolo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9030762/
https://www.ncbi.nlm.nih.gov/pubmed/35458399
http://dx.doi.org/10.3390/v14040669