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Escalated (Dependent) Oxycodone Self-Administration Is Associated with Cognitive Impairment and Transcriptional Evidence of Neurodegeneration in Human Immunodeficiency Virus (HIV) Transgenic Rats
Substance use disorder is associated with accelerated disease progression in people with human immunodeficiency virus (HIV; PWH). Problem opioid use, including high-dose opioid therapy, prescription drug misuse, and opioid abuse, is high and increasing in the PWH population. Oxycodone is a broadly p...
Autores principales: | Fu, Yu, Lorrai, Irene, Zorman, Barry, Mercatelli, Daniele, Shankula, Chase, Marquez Gaytan, Jorge, Lefebvre, Celine, de Guglielmo, Giordano, Kim, Hyunjae Ryan, Sumazin, Pavel, Giorgi, Federico M., Repunte-Canonigo, Vez, Sanna, Pietro Paolo |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9030762/ https://www.ncbi.nlm.nih.gov/pubmed/35458399 http://dx.doi.org/10.3390/v14040669 |
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