Gdnf Acts as a Germ Cell-Derived Growth Factor and Regulates the Zebrafish Germ Stem Cell Niche in Autocrine- and Paracrine-Dependent Manners

Glial cell line-derived neurotrophic factor (GDNF) and its receptor (GDNF Family Receptor α1-GFRα1) are well known to mediate spermatogonial stem cell (SSC) proliferation and survival in mammalian testes. In nonmammalian species, Gdnf and Gfrα1 orthologs have been found but their functions remain po...

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Detalles Bibliográficos
Autores principales: Doretto, Lucas B., Butzge, Arno J., Nakajima, Rafael T., Martinez, Emanuel R. M., de Souza, Beatriz Marques, Rodrigues, Maira da Silva, Rosa, Ivana F., Ricci, Juliana M. B., Tovo-Neto, Aldo, Costa, Daniel F., Malafaia, Guilherme, Shao, Changwei, Nóbrega, Rafael H.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9030868/
https://www.ncbi.nlm.nih.gov/pubmed/35455974
http://dx.doi.org/10.3390/cells11081295

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9030868/
https://www.ncbi.nlm.nih.gov/pubmed/35455974
http://dx.doi.org/10.3390/cells11081295

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