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Dual Role of HIV-1 Envelope Signal Peptide in Immune Evasion

HIV-1 Env signal peptide (SP) is an important contributor to Env functions. Env is generated from Vpu/Env encoded bicistronic mRNA such that the 5′ end of Env-N-terminus, that encodes for Env-SP overlaps with 3′ end of Vpu. Env SP displays high sequence diversity, which translates into high variabil...

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Detalles Bibliográficos
Autores principales: Upadhyay, Chitra, Rao, Priyanka Gadam, Feyznezhad, Roya
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9030904/
https://www.ncbi.nlm.nih.gov/pubmed/35458538
http://dx.doi.org/10.3390/v14040808