RT-QuIC and Related Assays for Detecting and Quantifying Prion-like Pathological Seeds of α-Synuclein

Various disease-associated forms or strains of α-synuclein (αSyn(D)) can spread and accumulate in a prion-like fashion during synucleinopathies such as Parkinson’s disease (PD), Lewy body dementia (DLB), and multiple system atrophy (MSA). This capacity for self-propagation has enabled the developmen...

Descripción completa

Detalles Bibliográficos
Autores principales: Srivastava, Ankit, Alam, Parvez, Caughey, Byron
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9030929/
https://www.ncbi.nlm.nih.gov/pubmed/35454165
http://dx.doi.org/10.3390/biom12040576

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9030929/
https://www.ncbi.nlm.nih.gov/pubmed/35454165
http://dx.doi.org/10.3390/biom12040576

Ejemplares similares