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Blockade of TASK-1 Channel Improves the Efficacy of Levetiracetam in Chronically Epileptic Rats
Tandem of P domains in a weak inwardly rectifying K(+) channel (TWIK)-related acid sensitive K(+)-1 channel (TASK-1) is an outwardly rectifying K(+) channel that acts in response to extracellular pH. TASK-1 is upregulated in the astrocytes (particularly in the CA1 region) of the hippocampi of patien...
Autores principales: | , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9030960/ https://www.ncbi.nlm.nih.gov/pubmed/35453538 http://dx.doi.org/10.3390/biomedicines10040787 |