Cargando…

Blockade of TASK-1 Channel Improves the Efficacy of Levetiracetam in Chronically Epileptic Rats

Tandem of P domains in a weak inwardly rectifying K(+) channel (TWIK)-related acid sensitive K(+)-1 channel (TASK-1) is an outwardly rectifying K(+) channel that acts in response to extracellular pH. TASK-1 is upregulated in the astrocytes (particularly in the CA1 region) of the hippocampi of patien...

Descripción completa

Detalles Bibliográficos
Autores principales:	Kim, Ji-Eun, Kang, Tae-Cheon
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2022
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9030960/ https://www.ncbi.nlm.nih.gov/pubmed/35453538 http://dx.doi.org/10.3390/biomedicines10040787

Ejemplares similares

PTEN Is Required for The Anti-Epileptic Effects of AMPA Receptor Antagonists in Chronic Epileptic Rats
por: Kim, Ji-Eun, et al.
Publicado: (2020)

Levetiracetam Versus Levetiracetam Plus Sodium Channel Blockers for Postoperative Epileptic Seizure Prevention in Brain Tumor Patients
por: Watanabe, Noriyuki, et al.
Publicado: (2022)

Use of Levetiracetam in Epileptic Dogs with Chronic Kidney Disease: A Retrospective Study
por: Gim, So-Yeon, et al.
Publicado: (2021)

Levetiracetam in the Treatment of Epileptic Seizures After Liver Transplantation
por: Lin, Chih-Hsiang, et al.
Publicado: (2015)

Deregulation of Astroglial TASK-1 K(+) Channel Decreases the Responsiveness to Perampanel-Induced AMPA Receptor Inhibition in Chronic Epilepsy Rats
por: Lee, Duk-Shin, et al.
Publicado: (2023)

Levetiracetam Therapeutic Drug Monitoring in a Large Cohort of Korean Epileptic Patients
por: Ha, Changhee, et al.
Publicado: (2021)

Perampanel Affects Up-Stream Regulatory Signaling Pathways of GluA1 Phosphorylation in Normal and Epileptic Rats
por: Kim, Ji-Eun, et al.
Publicado: (2019)

Evaluation of the Levetiracetam treatment on reduction of epileptic discharges in electroencephalogram in children with epilepsy
por: FAYYAZI, Afshin, et al.
Publicado: (2021)

Clinical Application of Pharmacokinetics to Appraise Adherence to Levetiracetam in Portuguese Epileptic Patients
por: Silva, Rui, et al.
Publicado: (2022)

Impact of ABCB1 Polymorphism on Levetiracetam Serum Concentrations in Epileptic Uygur Children in China
por: Zhao, Ting, et al.
Publicado: (2020)

Acute Liver Failure Associated with Levetiracetam and Lacosamide Combination Treatment for Unspecified Epileptic Disorder
por: Gutiérrez-Grobe, Ylse, et al.
Publicado: (2013)

Effect of levetiracetam drug on antioxidant and liver enzymes in epileptic patients: case-control study
por: Mahdavi, Atena, et al.
Publicado: (2020)

Efficacy of levetiracetam for neonatal seizures in preterm infants
por: Han, Ji Yoon, et al.
Publicado: (2018)

Population pharmacokinetics of extended‐release levetiracetam in epileptic dogs when administered alone, with phenobarbital or zonisamide
por: Muñana, Karen R., et al.
Publicado: (2018)

Pharmacokinetic Monitoring of Levetiracetam in Portuguese Refractory Epileptic Patients: Effect of Gender, Weight and Concomitant Therapy
por: Silva, Rui, et al.
Publicado: (2020)

Efficacy and Tolerability of Intravenous Levetiracetam in Children
por: Aceves, Jose, et al.
Publicado: (2013)

Efficacy of Levetiracetam in Treatment of Childhood Stuttering
por: Ghazavi, Mohammadreza, et al.
Publicado: (2020)

L-Type calcium channel blockade reduces network activity in human epileptic hypothalamic hamartoma tissue
por: Simeone, Kristina A, et al.
Publicado: (2011)

Blockade of AMPA Receptor Regulates Mitochondrial Dynamics by Modulating ERK1/2 and PP1/PP2A-Mediated DRP1-S616 Phosphorylations in the Normal Rat Hippocampus
por: Kim, Ji-Eun, et al.
Publicado: (2019)

Peroxiredoxin 6 Regulates Glutathione Peroxidase 1-Medited Glutamine Synthase Preservation in the Hippocampus of Chronic Epilepsy Rats
por: Kim, Ji-Eun, et al.
Publicado: (2023)

Inhibition of AKT/GSK3β/CREB Pathway Improves the Responsiveness to AMPA Receptor Antagonists by Regulating GRIA1 Surface Expression in Chronic Epilepsy Rats
por: Kim, Ji-Eun, et al.
Publicado: (2021)

Efficacy and safety of levetiracetam in the management of seizures in neonates
por: Sedighi, Mostafa, et al.
Publicado: (2016)

Levetiracetam/midazolam: Lack of efficacy: case report
Publicado: (2021)

Treadmill exercise improves memory function by inhibiting hippocampal apoptosis in pilocarpine-induced epileptic rats
por: Lee, Jae-Min, et al.
Publicado: (2018)

Assessment of the biomarkers of hepatotoxicity following carbamazepine, levetiracetam, and carbamazepine-levetiracetam adjunctive treatment in male Wistar rats
por: Osuntokun, Opeyemi Samson, et al.
Publicado: (2021)

The Blockade of Store-Operated Calcium Channels Improves Decompression Sickness in Rats
por: Tang, Shih-En, et al.
Publicado: (2020)

CDDO-Me Attenuates Astroglial Autophagy via Nrf2-, ERK1/2-SP1- and Src-CK2-PTEN-PI3K/AKT-Mediated Signaling Pathways in the Hippocampus of Chronic Epilepsy Rats
por: Kim, Ji-Eun, et al.
Publicado: (2021)

The efficacy and side effects of levetiracetam on refractory epilepsy in children
por: Incecik, Faruk, et al.
Publicado: (2012)

Efficacy and Safety of Levetiracetam and Carbamazepine as Monotherapy in Partial Seizures
por: Suresh, Swaroop Hassan, et al.
Publicado: (2015)

Levetiracetam/lorazepam/phenytoin: Lack of efficacy: case report
Publicado: (2021)

Levetiracetam/sodium valproate: Lack of efficacy: case report
Publicado: (2022)

Lacosamide/levetiracetam/valproate: Lack of efficacy: case report
Publicado: (2022)

Blockade of 67-kDa Laminin Receptor Facilitates AQP4 Down-Regulation and BBB Disruption via ERK1/2-and p38 MAPK-Mediated PI3K/AKT Activations
por: Kim, Ji-Eun, et al.
Publicado: (2020)

Sp1-Mediated Prdx6 Upregulation Leads to Clasmatodendrosis by Increasing Its aiPLA2 Activity in the CA1 Astrocytes in Chronic Epilepsy Rats
por: Kim, Ji-Eun, et al.
Publicado: (2022)

TASK‐1 channel blockade by AVE1231 increases vasocontractile responses and BP in 1‐ to 2‐week‐old but not adult rats
por: Shvetsova, Anastasia A., et al.
Publicado: (2020)

Effect of date molasses on levetiracetam pharmacokinetics in healthy rats
por: Abu Dayyih, Wael, et al.
Publicado: (2023)

Angiotensin II AT(1) Receptor Blockade Changes Expression of Renal Sodium Transporters in Rats with Chronic Renal Failure
por: Kim, Eun-Jung, et al.
Publicado: (2005)

Intravenous levetiracetam versus phenobarbital in children with status epilepticus or acute repetitive seizures
por: Lee, Yun-Jeong, et al.
Publicado: (2016)

Blockade of BK channels attenuates chronic visceral hypersensitivity in an IBS-like rat model
por: Fan, F, et al.
Publicado: (2021)

Levetiracetam improves disinhibitory behavior in nonconvulsive status epilepticus
por: Yamamuro, Kazuhiko, et al.
Publicado: (2014)

Cannot write session to /tmp/vufind_sessions/sess_rff3cm5dko96qenco42mprilc7