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Peptide Bond Formation between Aminoacyl-Minihelices by a Scaffold Derived from the Peptidyl Transferase Center

The peptidyl transferase center (PTC) in the ribosome is composed of two symmetrically arranged tRNA-like units that contribute to peptide bond formation. We prepared units of the PTC components with putative tRNA-like structure and attempted to obtain peptide bond formation between aminoacyl-minihe...

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Detalles Bibliográficos
Autores principales: Kawabata, Mai, Kawashima, Kentaro, Mutsuro-Aoki, Hiromi, Ando, Tadashi, Umehara, Takuya, Tamura, Koji
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9030986/
https://www.ncbi.nlm.nih.gov/pubmed/35455064
http://dx.doi.org/10.3390/life12040573