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Population Pharmacokinetics of Valproic Acid in Pediatric and Adult Caucasian Patients

(1) Background: The aim of this study was to explore the valproic acid (VPA) pharmacokinetic characteristics in a large population of pediatric and adult Caucasian patients and to establish a robust population pharmacokinetic (PopPK) model. (2) Methods: A total of 2527 serum VPA samples collected fr...

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Detalles Bibliográficos
Autores principales: Teixeira-da-Silva, Paulo, Pérez-Blanco, Jonás Samuel, Santos-Buelga, Dolores, Otero, María José, García, María José
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9031051/
https://www.ncbi.nlm.nih.gov/pubmed/35456645
http://dx.doi.org/10.3390/pharmaceutics14040811