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Insect Cells for High-Yield Production of SARS-CoV-2 Spike Protein: Building a Virosome-Based COVID-19 Vaccine Candidate

The severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) homotrimeric spike (S) protein is responsible for mediating host cell entry by binding to the angiotensin-converting enzyme 2 (ACE2) receptor, thus being a key viral antigen to target in a coronavirus disease 19 (COVID-19) vaccine. Des...

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Detalles Bibliográficos
Autores principales: Fernandes, Bárbara, Castro, Rute, Bhoelan, Farien, Bemelman, Denzel, Gomes, Ricardo A., Costa, Júlia, Gomes-Alves, Patrícia, Stegmann, Toon, Amacker, Mario, Alves, Paula M., Fleury, Sylvain, Roldão, António
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9031128/
https://www.ncbi.nlm.nih.gov/pubmed/35456687
http://dx.doi.org/10.3390/pharmaceutics14040854