A Novel Anti-CD73 Antibody That Selectively Inhibits Membrane CD73 Shows Antitumor Activity and Induces Tumor Immune Escape

CD73 catalyzes the conversion of ATP to adenosine, which is involved in various physiological and pathological processes, including tumor immune escape. Because CD73 expression and activity are particularly high on cancer cells and contribute to the immunosuppressive properties of the tumor environm...

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Detalles Bibliográficos
Autores principales: Kellner, Markus, von Neubeck, Bettina, Czogalla, Bastian, Feederle, Regina, Vick, Binje, Jeremias, Irmela, Zeidler, Reinhard
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9031174/
https://www.ncbi.nlm.nih.gov/pubmed/35453575
http://dx.doi.org/10.3390/biomedicines10040825

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9031174/
https://www.ncbi.nlm.nih.gov/pubmed/35453575
http://dx.doi.org/10.3390/biomedicines10040825

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