Computational Insights and In Vitro Validation of Antibacterial Potential of Shikimate Pathway-Derived Phenolic Acids as NorA Efflux Pump Inhibitors

The expression of the efflux pump systems is the most important mechanism of antibiotic resistance in bacteria, as it contributes to reduced concentration and the subsequent inactivity of administered antibiotics. NorA is one of the most studied antibacterial targets used as a model for efflux-media...

Descripción completa

Detalles Bibliográficos
Autores principales: Singh, Karishma, Coopoosamy, Roger M., Gumede, Njabulo J., Sabiu, Saheed
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9031328/
https://www.ncbi.nlm.nih.gov/pubmed/35458799
http://dx.doi.org/10.3390/molecules27082601

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9031328/
https://www.ncbi.nlm.nih.gov/pubmed/35458799
http://dx.doi.org/10.3390/molecules27082601

Ejemplares similares