Microfluidics Formulated Liposomes of Hypoxia Activated Prodrug for Treatment of Pancreatic Cancer

Pancreatic ductal adenocarcinoma (PDAC) presents as an unmet clinical challenge for drug delivery due to its unique hypoxic biology. Vinblastine-N-Oxide (CPD100) is a hypoxia-activated prodrug (HAP) that selectively converts to its parent compound, vinblastine, a potent cytotoxic agent, under oxygen...

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Detalles Bibliográficos
Autores principales: Shah, Vidhi M., Dorrell, Craig, Al-Fatease, Adel, Allen-Petersen, Brittany L., Woo, Yeonhee, Bortnyak, Yuliya, Gheewala, Rohi, Sheppard, Brett C., Sears, Rosalie C., Alani, Adam WG.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9031349/
https://www.ncbi.nlm.nih.gov/pubmed/35456547
http://dx.doi.org/10.3390/pharmaceutics14040713

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9031349/
https://www.ncbi.nlm.nih.gov/pubmed/35456547
http://dx.doi.org/10.3390/pharmaceutics14040713

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