Immune Modulating Brevetoxins: Monocyte Cytotoxicity, Apoptosis, and Activation of M1/M2 Response Elements Is Dependent on Reactive Groups

Brevetoxins are a suite of marine neurotoxins that activate voltage-gated sodium channels (VGSCs) in cell membranes, with toxicity occurring from persistent activation of the channel at high doses. Lower doses, in contrast, have been shown to elicit neuroregeneration. Brevetoxins have thus been prop...

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Detalles Bibliográficos
Autores principales: McCall, Jennifer R., Sausman, Kathryn T., Keeler, Devon M., Brown, Ariel P., Turrise, Stephanie L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9031394/
https://www.ncbi.nlm.nih.gov/pubmed/35447906
http://dx.doi.org/10.3390/md20040233

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9031394/
https://www.ncbi.nlm.nih.gov/pubmed/35447906
http://dx.doi.org/10.3390/md20040233

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