Novel Mutations in Putative Nicotinic Acid Phosphoribosyltransferases of Mycobacterium tuberculosis and Their Effect on Protein Thermodynamic Properties

pncB1 and pncB2 are two putative nicotinic acid phosphoribosyltransferases, playing a role in cofactor salvage and drug resistance in Mycobacterium tuberculosis. Mutations have been reported in first- and second-line drug targets, causing resistance. However, pncB1 and pncB2 mutational data are not...

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Detalles Bibliográficos
Autores principales: Zhang, Yu-Juan, Khan, Muhammad Tahir, Lodhi, Madeeha Shahzad, Al-Amrah, Hadba, Alrdahe, Salma Saleh, Alatawi, Hanan Ali, Darwish, Doaa Bahaa Eldin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9031469/
https://www.ncbi.nlm.nih.gov/pubmed/35458373
http://dx.doi.org/10.3390/polym14081623

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9031469/
https://www.ncbi.nlm.nih.gov/pubmed/35458373
http://dx.doi.org/10.3390/polym14081623

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