Cargando…

Novel Mutations in Putative Nicotinic Acid Phosphoribosyltransferases of Mycobacterium tuberculosis and Their Effect on Protein Thermodynamic Properties

pncB1 and pncB2 are two putative nicotinic acid phosphoribosyltransferases, playing a role in cofactor salvage and drug resistance in Mycobacterium tuberculosis. Mutations have been reported in first- and second-line drug targets, causing resistance. However, pncB1 and pncB2 mutational data are not...

Descripción completa

Detalles Bibliográficos
Autores principales:	Zhang, Yu-Juan, Khan, Muhammad Tahir, Lodhi, Madeeha Shahzad, Al-Amrah, Hadba, Alrdahe, Salma Saleh, Alatawi, Hanan Ali, Darwish, Doaa Bahaa Eldin
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2022
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9031469/ https://www.ncbi.nlm.nih.gov/pubmed/35458373 http://dx.doi.org/10.3390/polym14081623

Ejemplares similares

Changes in Metabolite Profiling and Expression Levels of Key Genes Involved in the Terpenoid Biosynthesis Pathway in Garden Sage (Salvia officinalis) under the Effect of Hydrazine Hydrate
por: Ali, Mohammed, et al.
Publicado: (2023)

Emerging mutations in envelope protein of SARS-CoV-2 and their effect on thermodynamic properties
por: Mou, Kejie, et al.
Publicado: (2021)

Innovative Artificial-Intelligence- Based Approach for the Biodegradation of Feather Keratin by Bacillus paramycoides, and Cytotoxicity of the Resulting Amino Acids
por: Moussa, Zeiad, et al.
Publicado: (2021)

Direct and Indirect Selection for Grain Yield and Grain Weight in Late Generations of Bread Wheat under Drought Stress and Normal Irrigation Environments
por: Mahdy, Rasha E., et al.
Publicado: (2022)

Crystal structure of human nicotinic acid phosphoribosyltransferase
por: Marletta, Ada Serena, et al.
Publicado: (2015)

Overexpression of Terpenoid Biosynthesis Genes Modifies Root Growth and Nodulation in Soybean (Glycine max)
por: Ali, Mohammed, et al.
Publicado: (2022)

Crystal Structure of Sus scrofa Quinolinate Phosphoribosyltransferase in Complex with Nicotinate Mononucleotide
por: Youn, Hyung-Seop, et al.
Publicado: (2013)

Extensive regulation of nicotinate phosphoribosyltransferase (NAPRT) expression in human tissues and tumors
por: Duarte-Pereira, Sara, et al.
Publicado: (2015)

A Versatile Continuous Fluorometric Enzymatic Assay for Targeting Nicotinate Phosphoribosyltransferase
por: Minazzato, Gabriele, et al.
Publicado: (2023)

Biochemical Characterization of Uracil Phosphoribosyltransferase from Mycobacterium tuberculosis
por: Villela, Anne Drumond, et al.
Publicado: (2013)

Alleviation of Lead Stress on Sage Plant by 5-Aminolevulinic Acid (ALA)
por: El-Shora, Hamed M., et al.
Publicado: (2021)

Extracellular nicotinate phosphoribosyltransferase binds Toll like receptor 4 and mediates inflammation
por: Managò, Antonella, et al.
Publicado: (2019)

Attributes of intestinal microbiota composition and their correlation with clinical primary non-response to anti-TNF-α agents in inflammatory bowel disease patients
por: Alatawi, Hanan, et al.
Publicado: (2022)

Composition of the gut microbiota in patients with inflammatory bowel disease in Saudi Arabia: A pilot study
por: Al-Amrah, Hadba, et al.
Publicado: (2023)

Properly Substituted Benzimidazoles as a New Promising Class of Nicotinate Phosphoribosyltransferase (NAPRT) Modulators
por: Baldassarri, Cecilia, et al.
Publicado: (2023)

Overexpression of Terpenoid Biosynthesis Genes From Garden Sage (Salvia officinalis) Modulates Rhizobia Interaction and Nodulation in Soybean
por: Ali, Mohammed, et al.
Publicado: (2021)

Coronavirus Genomes and Unique Mutations in Structural and Non-Structural Proteins in Pakistani SARS-CoV-2 Delta Variants during the Fourth Wave of the Pandemic
por: Anwar, Muhammad Zeeshan, et al.
Publicado: (2022)

Definitive Screening Design and Artificial Neural Network for Modeling a Rapid Biodegradation of Date Palm Fronds by a New Trichoderma sp. PWN6 into Citric Acid
por: Elsayed, Maha S., et al.
Publicado: (2021)

Mycobacterium tuberculosis Phosphoribosyltransferase Promotes Bacterial Survival in Macrophages by Inducing Histone Hypermethylation in Autophagy-Related Genes
por: Sengupta, Srabasti, et al.
Publicado: (2021)

Inhibition Mechanism of Methicillin-Resistant Staphylococcus aureus by Zinc Oxide Nanorods via Suppresses Penicillin-Binding Protein 2a
por: Hassan, Amr, et al.
Publicado: (2023)

Structure, mechanism and inhibition of anthranilate phosphoribosyltransferase
por: Scully, Thomas W., et al.
Publicado: (2023)

Cloning and Characterization of 1,8-Cineole Synthase (SgCINS) Gene From the Leaves of Salvia guaranitica Plant
por: Ali, Mohammed, et al.
Publicado: (2022)

Structural investigations on orotate phosphoribosyltransferase from Mycobacterium tuberculosis, a key enzyme of the de novo pyrimidine biosynthesis
por: Donini, Stefano, et al.
Publicado: (2017)

Microbial Degradation, Spectral analysis and Toxicological Assessment of Malachite Green Dye by Streptomyces exfoliatus
por: Abu-Hussien, Samah H., et al.
Publicado: (2022)

Mechanism of Feedback Allosteric Inhibition of ATP Phosphoribosyltransferase
por: Pedreño, Sònia, et al.
Publicado: (2012)

Nicotinamide phosphoribosyltransferase leukocyte overexpression in Graves’ opthalmopathy
por: Sawicka-Gutaj, Nadia, et al.
Publicado: (2016)

Adenine Phosphoribosyltransferase Deficiency Due to Novel Mutation
por: Ceballos-Picot, Irène, et al.
Publicado: (2018)

A Novel Method of Magnetic Nanoparticles Functionalized with Anti-Folate Receptor Antibody and Methotrexate for Antibody Mediated Targeted Drug Delivery
por: Lodhi, Madeeha Shahzad, et al.
Publicado: (2022)

Constitutive overexpression of GsIMaT2 gene from wild soybean enhances rhizobia interaction and increase nodulation in soybean (Glycine max)
por: Darwish, Doaa Bahaa Eldin, et al.
Publicado: (2022)

Biochemical Characterization of Quinolinic Acid Phosphoribosyltransferase from Mycobacterium tuberculosis H37Rv and Inhibition of Its Activity by Pyrazinamide
por: Kim, Hyun, et al.
Publicado: (2014)

Influence of silicon nano-particles on Avena sativa L. to alleviate the biotic stress of Rhizoctonia solani
por: Ahmad, Faiza, et al.
Publicado: (2023)

Crystal structure of Leishmania tarentolae hypoxanthine-guanine phosphoribosyltransferase
por: Monzani, Paulo S, et al.
Publicado: (2007)

Expression of thymidylate synthase and orotate phosphoribosyltransferase in thymic carcinoma
por: YOKOTA, KEISUKE, et al.
Publicado: (2012)

Extracellular nicotinamide phosphoribosyltransferase, a new cancer metabokine
por: Grolla, Ambra A, et al.
Publicado: (2016)

Metabolic and molecular insights into an essential role of nicotinamide phosphoribosyltransferase
por: Zhang, Li Q, et al.
Publicado: (2017)

Phosphoribosyltransferases and Their Roles in Plant Development and Abiotic Stress Response
por: Liu, Ye, et al.
Publicado: (2023)

Optimization of Heavy Metals Biosorption via Artificial Neural Network: A Case Study of Cobalt (II) Sorption by Pseudomonas alcaliphila NEWG-2
por: Elsayed, Ashraf, et al.
Publicado: (2022)

Synthesis, characterization and anti-breast cancer potential of an incensole acetate nanoemulsion from Catharanthus roseus essential oil; in silico, in vitro, and in vivo study
por: Nayila, Iffat, et al.
Publicado: (2023)

Probing Transferrin Receptor Overexpression in Gastric Cancer Mice Models
por: Lodhi, Madeeha Shahzad, et al.
Publicado: (2021)

Nicotinamide Phosphoribosyltransferase May Be Involved in Age-Related Brain Diseases
por: Liu, Li-Ying, et al.
Publicado: (2012)

Cannot write session to /tmp/vufind_sessions/sess_qg1vmp0enf29lrtbpv8hmdl318