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Independent and Interactive Effects of Genetic Background and Sex on Tissue Metabolomes of Adipose, Skeletal Muscle, and Liver in Mice

Genetics play an important role in the development of metabolic diseases. However, the relative influence of genetic variation on metabolism is not well defined, particularly in tissues, where metabolic dysfunction that leads to disease occurs. We used inbred strains of laboratory mice to evaluate t...

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Detalles Bibliográficos
Autores principales: Wells, Ann E., Barrington, William T., Dearth, Stephen, Milind, Nikhil, Carter, Gregory W., Threadgill, David W., Campagna, Shawn R., Voy, Brynn H.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9031494/
https://www.ncbi.nlm.nih.gov/pubmed/35448524
http://dx.doi.org/10.3390/metabo12040337