Deficiency of Thyroid Hormone Reduces Voltage-Gated Na(+) Currents as Well as Expression of Na(+)/K(+)-ATPase in the Mouse Hippocampus

Mice lacking functional thyroid follicular cells, Pax8(−/−) mice, die early postnatally, making them suitable models for extreme hypothyroidism. We have previously obtained evidence in postnatal rat neurons, that a down-regulation of Na(+)-current density could explain the reduced excitability of th...

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Detalles Bibliográficos
Autores principales: Sundaram, Sivaraj Mohana, Marx, Romy, Lesslich, Heiko M., Dietzel, Irmgard D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Communication
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9031557/
https://www.ncbi.nlm.nih.gov/pubmed/35456949
http://dx.doi.org/10.3390/ijms23084133

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9031557/
https://www.ncbi.nlm.nih.gov/pubmed/35456949
http://dx.doi.org/10.3390/ijms23084133

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