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Deficiency of Thyroid Hormone Reduces Voltage-Gated Na(+) Currents as Well as Expression of Na(+)/K(+)-ATPase in the Mouse Hippocampus
Mice lacking functional thyroid follicular cells, Pax8(−/−) mice, die early postnatally, making them suitable models for extreme hypothyroidism. We have previously obtained evidence in postnatal rat neurons, that a down-regulation of Na(+)-current density could explain the reduced excitability of th...
| Autores principales: | , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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MDPI
2022
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9031557/ https://www.ncbi.nlm.nih.gov/pubmed/35456949 http://dx.doi.org/10.3390/ijms23084133 |