A Non-Hazardous Deparaffinization Protocol Enables Quantitative Proteomics of Core Needle Biopsy-Sized Formalin-Fixed and Paraffin-Embedded (FFPE) Tissue Specimens

Most human tumor tissues that are obtained for pathology and diagnostic purposes are formalin-fixed and paraffin-embedded (FFPE). To perform quantitative proteomics of FFPE samples, paraffin has to be removed and formalin-induced crosslinks have to be reversed prior to proteolytic digestion. A centr...

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Detalles Bibliográficos
Autores principales: Mitsa, Georgia, Guo, Qianyu, Goncalves, Christophe, Preston, Samuel E. J., Lacasse, Vincent, Aguilar-Mahecha, Adriana, Benlimame, Naciba, Basik, Mark, Spatz, Alan, Batist, Gerald, Miller, Wilson H., del Rincon, Sonia V., Zahedi, René P., Borchers, Christoph H.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9031572/
https://www.ncbi.nlm.nih.gov/pubmed/35457260
http://dx.doi.org/10.3390/ijms23084443

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9031572/
https://www.ncbi.nlm.nih.gov/pubmed/35457260
http://dx.doi.org/10.3390/ijms23084443

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