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NRF2 Alters Mitochondrial Gene Expression in Neonate Mice Exposed to Hyperoxia

Approximately 1 in 10 newborns are born preterm and require supplemental oxygen (O(2)) in an extrauterine environment following birth. Supplemental O(2) can induce oxidative stress that can impair mitochondrial function, resulting in lung injury and increased risk in early life pulmonary diseases. T...

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Detalles Bibliográficos
Autores principales: Vellers, Heather L., Cho, Hye-Youn, Gladwell, Wesley, Gerrish, Kevin, Santos, Janine H., Ofman, Gaston, Miller-DeGraff, Laura, Mahler, T. Beth, Kleeberger, Steven R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9031618/
https://www.ncbi.nlm.nih.gov/pubmed/35453445
http://dx.doi.org/10.3390/antiox11040760